Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

Blog Article

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of a number of myeloma. Its synthesis or research is vital for ensuring the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets particular kinds of most cancers, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers including breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their study is crucial for optimizing the manufacturing procedure and making sure substantial purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is utilized to deal with breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the cure of breast cancer. Various intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug effective in managing cancers including ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the remedy of colorectal most cancers 3-triacetate and tiny mobile lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, which have different apps, together with antiviral properties.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-4 to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): Cb 7598 This compound is involved with the synthesis of varied gluconic acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle variety 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).